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Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment

The plant metabolite andrographolide induces cell cycle arrest and apoptosis in cancer cells. The mechanism(s) by which andrographolide induces apoptosis however, have not been elucidated. The present study was performed to determine the molecular events that promote apoptosis in andrographolide tre...

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Detalles Bibliográficos
Autores principales: Banerjee, Aditi, Ahmed, Hafiz, Yang, Peixin, Czinn, Steven J., Blanchard, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173070/
https://www.ncbi.nlm.nih.gov/pubmed/27166181
http://dx.doi.org/10.18632/oncotarget.9180