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Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment
The plant metabolite andrographolide induces cell cycle arrest and apoptosis in cancer cells. The mechanism(s) by which andrographolide induces apoptosis however, have not been elucidated. The present study was performed to determine the molecular events that promote apoptosis in andrographolide tre...
Autores principales: | Banerjee, Aditi, Ahmed, Hafiz, Yang, Peixin, Czinn, Steven J., Blanchard, Thomas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173070/ https://www.ncbi.nlm.nih.gov/pubmed/27166181 http://dx.doi.org/10.18632/oncotarget.9180 |
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