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RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma

Small Rho GTPase (Rho) and its immediate effector Rho kinase (ROCK) are reported to regulate cell survival, but the detailed molecular mechanism remains largely unknown. We had previously shown that Rho/ROCK signaling was highly activated in hepatocellular carcinoma (HCC). In this study, we further...

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Detalles Bibliográficos
Autores principales: Ma, Wei, Sze, Karen Man-Fong, Chan, Lo Kong, Lee, Joyce Man-Fong, Wei, Larry Lai, Wong, Chun-Ming, Lee, Terence Kin-Wah, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173071/
https://www.ncbi.nlm.nih.gov/pubmed/27213590
http://dx.doi.org/10.18632/oncotarget.9441