Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy

The capacity of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to selectively induce cell death in malignant cells triggered numerous attempts for therapeutic exploitation. In clinical trials, however, TRAIL did not live up to the expectations, as tumors exhibit high rates of TRAIL...

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Detalles Bibliográficos
Autores principales: Knoll, Gertrud, Bittner, Sebastian, Kurz, Maria, Jantsch, Jonathan, Ehrenschwender, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173074/
https://www.ncbi.nlm.nih.gov/pubmed/27166192
http://dx.doi.org/10.18632/oncotarget.9206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173074/
https://www.ncbi.nlm.nih.gov/pubmed/27166192
http://dx.doi.org/10.18632/oncotarget.9206

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