Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells

Deregulated STAT5 activity in the mammary gland causes parity-dependent tumorigenesis. Epithelial cell cultures transfected with constitutively active STAT5 express higher levels of the histone H2AX than their non-transfected counterparts. Higher H2AX expression may be involved in tumorigenesis. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Reichenstein, Moshe, Rauner, Gat, Kfir, Shenhav, Kisliouk, Tatiana, Barash, Itamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173096/
https://www.ncbi.nlm.nih.gov/pubmed/27260000
http://dx.doi.org/10.18632/oncotarget.9718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173096/
https://www.ncbi.nlm.nih.gov/pubmed/27260000
http://dx.doi.org/10.18632/oncotarget.9718

Ejemplares similares