Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination

Pellino-1 is an E3 ubiquitin ligase that mediates immune receptor signaling pathways. The role of Pellino-1 in oncogenesis of lung cancer was investigated in this study. Pellino-1 expression was increased in human lung cancer cell lines compared with non-neoplastic lung cell lines. Pellino-1 overexp...

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Detalles Bibliográficos
Autores principales: Jeon, Yoon Kyung, Kim, Chung Kwon, Koh, Jaemoon, Chung, Doo Hyun, Ha, Geun-Hyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173098/
https://www.ncbi.nlm.nih.gov/pubmed/27248820
http://dx.doi.org/10.18632/oncotarget.9619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173098/
https://www.ncbi.nlm.nih.gov/pubmed/27248820
http://dx.doi.org/10.18632/oncotarget.9619

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