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Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination
Pellino-1 is an E3 ubiquitin ligase that mediates immune receptor signaling pathways. The role of Pellino-1 in oncogenesis of lung cancer was investigated in this study. Pellino-1 expression was increased in human lung cancer cell lines compared with non-neoplastic lung cell lines. Pellino-1 overexp...
Autores principales: | Jeon, Yoon Kyung, Kim, Chung Kwon, Koh, Jaemoon, Chung, Doo Hyun, Ha, Geun-Hyoung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173098/ https://www.ncbi.nlm.nih.gov/pubmed/27248820 http://dx.doi.org/10.18632/oncotarget.9619 |
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