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The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts

The IL-6/STAT3/NF-κB positive feedback loop links inflammation to cancer and maintains cells at a transformed state. Similarly, cancer-associated myofibroblats remains active even in absence of cancer cells. However, the molecular basis of this sustained active state remains elusive. We have shown h...

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Detalles Bibliográficos
Autores principales: Hendrayani, Siti-Fauziah, Al-Harbi, Bothaina, Al-Ansari, Mysoon M., Silva, Gabriela, Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173109/
https://www.ncbi.nlm.nih.gov/pubmed/27248826
http://dx.doi.org/10.18632/oncotarget.9633