Cargando…

Direct cell fate conversion of human somatic stem cells into cone and rod photoreceptor-like cells by inhibition of microRNA-203

Stem cell-based photoreceptor differentiation strategies have been the recent focus of therapies for retinal degenerative diseases. Previous studies utilized embryonic stem (ES) cells and neural retina differentiation cocktails, including DKK1 and Noggin. Here, we show a novel microRNA-mediated stra...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Soon Won, Shin, Ji-Hee, Kim, Jae-Jun, Shin, Tae-Hoon, Seo, Yoojin, Kim, Hyung-Sik, Kang, Kyung-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173122/
https://www.ncbi.nlm.nih.gov/pubmed/27283900
http://dx.doi.org/10.18632/oncotarget.9882