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Direct cell fate conversion of human somatic stem cells into cone and rod photoreceptor-like cells by inhibition of microRNA-203
Stem cell-based photoreceptor differentiation strategies have been the recent focus of therapies for retinal degenerative diseases. Previous studies utilized embryonic stem (ES) cells and neural retina differentiation cocktails, including DKK1 and Noggin. Here, we show a novel microRNA-mediated stra...
Autores principales: | Choi, Soon Won, Shin, Ji-Hee, Kim, Jae-Jun, Shin, Tae-Hoon, Seo, Yoojin, Kim, Hyung-Sik, Kang, Kyung-Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173122/ https://www.ncbi.nlm.nih.gov/pubmed/27283900 http://dx.doi.org/10.18632/oncotarget.9882 |
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