MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis

Damage to mitochondria often results in the activation of both mitophagy and mitochondrial apoptosis. The elimination of dysfunctional mitochondria is necessary for mitochondrial quality maintenance and efficient energy supply. Here we report that miR-181a is a novel inhibitor of mitophagy. miR-181a...

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Detalles Bibliográficos
Autores principales: Cheng, Min, Liu, Lei, Lao, Yuanzhi, Liao, Weijie, Liao, Meijian, Luo, Xuan, Wu, Jiangbin, Xie, Weidong, Zhang, Yaou, Xu, Naihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173134/
https://www.ncbi.nlm.nih.gov/pubmed/27281615
http://dx.doi.org/10.18632/oncotarget.9786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173134/
https://www.ncbi.nlm.nih.gov/pubmed/27281615
http://dx.doi.org/10.18632/oncotarget.9786

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