Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein

The insulin-like growth factor-1 receptor (IGF-1R) is a receptor tyrosine kinase that has crucial roles in cell proliferation and protection from apoptosis. It is therefore not surprising that IGF-1R is often found overexpressed in many types of tumors. This has made IGF-1R a prominent target molecu...

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Detalles Bibliográficos
Autores principales: Warsito, Dudi, Lin, Yingbo, Gnirck, Ann-Christin, Sehat, Bita, Larsson, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173135/
https://www.ncbi.nlm.nih.gov/pubmed/27275536
http://dx.doi.org/10.18632/oncotarget.9785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173135/
https://www.ncbi.nlm.nih.gov/pubmed/27275536
http://dx.doi.org/10.18632/oncotarget.9785

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