CHES-1-like, the ortholog of a non-obstructive azoospermia-associated gene, blocks germline stem cell differentiation by upregulating Dpp expression in Drosophila testis

Azoospermia is a high risk factor for testicular germ cell tumors, whose underlying molecular mechanisms remain unknown. In a genome-wide association study to identify novel loci associated with human non-obstructive azoospermia (NOA), we uncovered a single nucleotide polymorphism (rs1887102, P=2.60...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Liu, Yujuan, Lan, Xiang, Wu, Hao, Wen, Yang, Zhou, Zuomin, Hu, Zhibin, Sha, Jiahao, Guo, Xuejiang, Tong, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173136/
https://www.ncbi.nlm.nih.gov/pubmed/27281616
http://dx.doi.org/10.18632/oncotarget.9789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173136/
https://www.ncbi.nlm.nih.gov/pubmed/27281616
http://dx.doi.org/10.18632/oncotarget.9789

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