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Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D

ErbB1 and ErbB2 are oncogenic cell surface receptor tyrosine kinases, linked to many forms of human cancer, and are major cancer therapeutic targets. Many lines of evidence indicate that targeting ErbB1 and ErbB2 is an important cancer therapeutic approach. We recently found that a recombinant enzym...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Li, Yun, Bhattacharya, Arup, Zhang, Yuesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173139/
https://www.ncbi.nlm.nih.gov/pubmed/27286447
http://dx.doi.org/10.18632/oncotarget.9851