Down-regulation of Krüppel-like factor-4 by microRNA-135a-5p promotes proliferation and metastasis in hepatocellular carcinoma by transforming growth factor-β1

Krüppel-like Factor-4 (KLF4) is a zinc finger transcription factor which plays an important role in cell cycle, proliferation and apoptosis. In Hepatocellular Carcinoma (HCC), the function of KLF4 has been characterized as tumor suppressor. However, the mechanism remains largely unknown. In this stu...

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Detalles Bibliográficos
Autores principales: Yao, Shanshan, Tian, Chuan, Ding, Youcheng, Ye, Qingwang, Gao, Yong, Yang, Ning, Li, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173156/
https://www.ncbi.nlm.nih.gov/pubmed/27302923
http://dx.doi.org/10.18632/oncotarget.9934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173156/
https://www.ncbi.nlm.nih.gov/pubmed/27302923
http://dx.doi.org/10.18632/oncotarget.9934

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