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Phase I study of pemetrexed with sorafenib in advanced solid tumors

PURPOSE: To determine if combination treatment with pemetrexed and sorafenib is safe and tolerable in patients with advanced solid tumors. RESULTS: Thirty-seven patients were enrolled and 36 patients were treated (24 in cohort A; 12 in cohort B). The cohort A dose schedule resulted in problematic cu...

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Detalles Bibliográficos
Autores principales: Poklepovic, Andrew, Gordon, Sarah, Shafer, Danielle A., Roberts, John D., Bose, Prithviraj, Geyer, Charles E., McGuire, William P., Tombes, Mary Beth, Shrader, Ellen, Strickler, Katie, Quigley, Maria, Wan, Wen, Kmieciak, Maciej, Massey, H. Davis, Booth, Laurence, Moran, Richard G., Dent, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173162/
https://www.ncbi.nlm.nih.gov/pubmed/27213589
http://dx.doi.org/10.18632/oncotarget.9434