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Phase I study of pemetrexed with sorafenib in advanced solid tumors
PURPOSE: To determine if combination treatment with pemetrexed and sorafenib is safe and tolerable in patients with advanced solid tumors. RESULTS: Thirty-seven patients were enrolled and 36 patients were treated (24 in cohort A; 12 in cohort B). The cohort A dose schedule resulted in problematic cu...
Autores principales: | Poklepovic, Andrew, Gordon, Sarah, Shafer, Danielle A., Roberts, John D., Bose, Prithviraj, Geyer, Charles E., McGuire, William P., Tombes, Mary Beth, Shrader, Ellen, Strickler, Katie, Quigley, Maria, Wan, Wen, Kmieciak, Maciej, Massey, H. Davis, Booth, Laurence, Moran, Richard G., Dent, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173162/ https://www.ncbi.nlm.nih.gov/pubmed/27213589 http://dx.doi.org/10.18632/oncotarget.9434 |
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