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FOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathways
FOXM1 is a pro-proliferative transcription factor that promotes cell cycle progression at the G1-S, and G2-M transitions. It is activated by phosphorylation usually mediated by successive cyclin – cyclin dependent kinase complexes, and is highly expressed in sarcoma. p53 down regulates FOXM1 and FOX...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173172/ https://www.ncbi.nlm.nih.gov/pubmed/27074562 http://dx.doi.org/10.18632/oncotarget.8669 |