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Predicting the Coupling Specificity of G-protein Coupled Receptors to G-proteins by Support Vector Machines

G-protein coupled receptors (GPCRs) represent one of the most important classes of drug targets for pharmaceutical industry and play important roles in cellular signal transduction. Predicting the coupling specificity of GPCRs to G-proteins is vital for further understanding the mechanism of signal...

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Detalles Bibliográficos
Autores principales: Guan, Cui-Ping, Jiang, Zhen-Ran, Zhou, Yan-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173181/
https://www.ncbi.nlm.nih.gov/pubmed/16689694
http://dx.doi.org/10.1016/S1672-0229(05)03035-4