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Predicting the Coupling Specificity of G-protein Coupled Receptors to G-proteins by Support Vector Machines
G-protein coupled receptors (GPCRs) represent one of the most important classes of drug targets for pharmaceutical industry and play important roles in cellular signal transduction. Predicting the coupling specificity of GPCRs to G-proteins is vital for further understanding the mechanism of signal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173181/ https://www.ncbi.nlm.nih.gov/pubmed/16689694 http://dx.doi.org/10.1016/S1672-0229(05)03035-4 |