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Targeting neuronal MAPK14/p38α activity to modulate autophagy in the Alzheimer disease brain

Dysregulated autophagic-lysosomal degradation of proteins has been linked to the most common genetic defect in familial Alzheimer disease, and has been correlated with disease progression in both human disease and in animal models. Recently, it was demonstrated that the expression of MAPK14/p38α pro...

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Detalles Bibliográficos
Autores principales: Alam, John, Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173254/
https://www.ncbi.nlm.nih.gov/pubmed/27715387
http://dx.doi.org/10.1080/15548627.2016.1238555