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Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development

Kidney formation involves patterning events that induce renal progenitors to form nephrons with an intricate composition of multiple segments. Here, we performed a chemical genetic screen using zebrafish and discovered that prostaglandins, lipid mediators involved in many physiological functions, in...

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Detalles Bibliográficos
Autores principales: Poureetezadi, Shahram Jevin, Cheng, Christina N, Chambers, Joseph M, Drummond, Bridgette E, Wingert, Rebecca A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173325/
https://www.ncbi.nlm.nih.gov/pubmed/27996936
http://dx.doi.org/10.7554/eLife.17551