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Self-Organizing Global Gene Expression Regulated through Criticality: Mechanism of the Cell-Fate Change
BACKGROUND: A fundamental issue in bioscience is to understand the mechanism that underlies the dynamic control of genome-wide expression through the complex temporal-spatial self-organization of the genome to regulate the change in cell fate. We address this issue by elucidating a physically motiva...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173342/ https://www.ncbi.nlm.nih.gov/pubmed/27997556 http://dx.doi.org/10.1371/journal.pone.0167912 |