Effects of neuromyelitis optica–IgG at the blood–brain barrier in vitro

OBJECTIVE: To address the hypothesis that physiologic interactions between astrocytes and endothelial cells (EC) at the blood–brain barrier (BBB) are afflicted by pathogenic inflammatory signaling when astrocytes are exposed to aquaporin-4 (AQP4) antibodies present in the immunoglobulin G (IgG) frac...

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Detalles Bibliográficos
Autores principales: Takeshita, Yukio, Obermeier, Birgit, Cotleur, Anne C., Spampinato, Simona F., Shimizu, Fumitaka, Yamamoto, Erin, Sano, Yasuteru, Kryzer, Thomas J., Lennon, Vanda A., Kanda, Takashi, Ransohoff, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173350/
https://www.ncbi.nlm.nih.gov/pubmed/28018943
http://dx.doi.org/10.1212/NXI.0000000000000311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173350/
https://www.ncbi.nlm.nih.gov/pubmed/28018943
http://dx.doi.org/10.1212/NXI.0000000000000311

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