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Effects of neuromyelitis optica–IgG at the blood–brain barrier in vitro

OBJECTIVE: To address the hypothesis that physiologic interactions between astrocytes and endothelial cells (EC) at the blood–brain barrier (BBB) are afflicted by pathogenic inflammatory signaling when astrocytes are exposed to aquaporin-4 (AQP4) antibodies present in the immunoglobulin G (IgG) frac...

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Detalles Bibliográficos
Autores principales:	Takeshita, Yukio, Obermeier, Birgit, Cotleur, Anne C., Spampinato, Simona F., Shimizu, Fumitaka, Yamamoto, Erin, Sano, Yasuteru, Kryzer, Thomas J., Lennon, Vanda A., Kanda, Takashi, Ransohoff, Richard M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173350/ https://www.ncbi.nlm.nih.gov/pubmed/28018943 http://dx.doi.org/10.1212/NXI.0000000000000311

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