Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

Low-density lipoprotein (LDL) is the major source of lipid within atherosclerotic lesions. Myeloperoxidase (MPO) is present in lesions and forms the reactive oxidants hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN). These oxidants modify LDL and have been strongly linked with the developme...

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Detalles Bibliográficos
Autores principales: Ismael, Fahd O., Barrett, Tessa J., Sheipouri, Diba, Brown, Bronwyn E., Davies, Michael J., Hawkins, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173366/
https://www.ncbi.nlm.nih.gov/pubmed/27997605
http://dx.doi.org/10.1371/journal.pone.0168844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173366/
https://www.ncbi.nlm.nih.gov/pubmed/27997605
http://dx.doi.org/10.1371/journal.pone.0168844

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