MUC13 Interaction with Receptor Tyrosine Kinase HER2 Drives Pancreatic Ductal Adenocarcinoma Progression

Although MUC13, a transmembrane mucin, is aberrantly expressed in pancreatic ductal adenocarcinoma (PDAC) and generally correlates with increased expression of HER2, the underlying mechanism remains poorly understood. Herein, we found that MUC13 co-localizes and interacts with HER2 in PDAC cells (re...

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Detalles Bibliográficos
Autores principales: Khan, Sheema, Sikander, Mohammed, Ebeling, Mara C., Ganju, Aditya, Kumari, Sonam, Yallapu, Murali M., Hafeez, Bilal Bin, Ise, Tomoko, Nagata, Satoshi, Zafar, Nadeem, Behrman, Stephen W., Wan, Jim Y., Ghimire, Hemendra M., Sahay, Peeyush, Pradhan, Prabhakar, Chauhan, Subhash C., Jaggi, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173450/
https://www.ncbi.nlm.nih.gov/pubmed/27321183
http://dx.doi.org/10.1038/onc.2016.218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173450/
https://www.ncbi.nlm.nih.gov/pubmed/27321183
http://dx.doi.org/10.1038/onc.2016.218

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