Cargando…

PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis

Atypical protein kinase Cι (PKCι) is an oncogene in lung and ovarian cancer. The PKCι gene PRKCI is targeted for frequent tumor-specific copy number gain (CNG) in both lung squamous cell carcinoma (LSCC) and ovarian serous carcinoma (OSC). We recently demonstrated that in LSCC cells PRKCI CNG functi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yin, Justilien, Verline, Brennan, Katharyn I., Jamieson, Lee, Murray, Nicole R., Fields, Alan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173453/
https://www.ncbi.nlm.nih.gov/pubmed/27321186
http://dx.doi.org/10.1038/onc.2016.224