Effect of various anticoagulants on the bioanalysis of drugs in rat blood: implication for pharmacokinetic studies of anticancer drugs

BACKGROUND: Pharmacokinetic studies are vital in development and optimization of drugs. While blood samples can be collected either in EDTA, heparin or citrate containing tubes for the estimation of drug levels in plasma, EDTA tubes are more commonly used. The purpose of this study was to evaluate t...

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Detalles Bibliográficos
Autores principales: Kulkarni, Preeti, Karanam, Ashwin, Gurjar, Murari, Dhoble, Sagar, Naik, Arvind B., Vidhun, Bhaskar H., Gota, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174014/
https://www.ncbi.nlm.nih.gov/pubmed/28053832
http://dx.doi.org/10.1186/s40064-016-3770-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174014/
https://www.ncbi.nlm.nih.gov/pubmed/28053832
http://dx.doi.org/10.1186/s40064-016-3770-4

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