Astragaloside IV Attenuates Podocyte Apoptosis Mediated by Endoplasmic Reticulum Stress through Upregulating Sarco/Endoplasmic Reticulum Ca(2+)-ATPase 2 Expression in Diabetic Nephropathy

Sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) plays a central role in the pathogenesis of diabetes. This protein has been recognized as a potential target for diabetic therapy. In this study, we identified astragaloside IV (AS-IV) as a potent modulator of SERCA inhibiting renal injury in diabeti...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Hengjiang, Cao, Aili, Chu, Shuang, Wang, Yi, Zang, Yingjun, Mao, Xiaodong, Wang, Hao, Wang, Yunman, Liu, Cheng, Zhang, Xuemei, Peng, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174081/
https://www.ncbi.nlm.nih.gov/pubmed/28066247
http://dx.doi.org/10.3389/fphar.2016.00500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174081/
https://www.ncbi.nlm.nih.gov/pubmed/28066247
http://dx.doi.org/10.3389/fphar.2016.00500

Ejemplares similares