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Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma

Regulatory T cells (Tregs) play an important role by controlling allergic inflammation of airways. Recently, it has been shown that statins have immunomodulatory properties, probably mediated by their effects on Tregs. Therefore, we evaluated the in vivo effect of atorvastatin (ATV) on Tregs and its...

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Detalles Bibliográficos
Autores principales: Blanquiceth, Yurany, Rodríguez-Perea, Ana Lucia, Tabares Guevara, Jorge H., Correa, Luis Alfonso, Sánchez, María Dulfary, Ramírez-Pineda, José Robinson, Velilla, Paula Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174085/
https://www.ncbi.nlm.nih.gov/pubmed/28066430
http://dx.doi.org/10.3389/fimmu.2016.00620