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Achaete-Scute Homolog 1 Expression Controls Cellular Differentiation of Neuroblastoma

Neuroblastoma, the major cause of infant cancer deaths, results from fast proliferation of undifferentiated neuroblasts. Treatment of high-risk neuroblastoma includes differentiation with retinoic acid (RA); however, the resistance of many of these tumors to RA-induced differentiation poses a consid...

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Detalles Bibliográficos
Autores principales: Kasim, Mumtaz, Heß, Vicky, Scholz, Holger, Persson, Pontus B., Fähling, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174122/
https://www.ncbi.nlm.nih.gov/pubmed/28066180
http://dx.doi.org/10.3389/fnmol.2016.00156