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FPOP-LC-MS/MS Suggests Differences in Interaction Sites of Amphipols and Detergents with Outer Membrane Proteins

Amphipols are a class of novel surfactants that are capable of stabilizing the native state of membrane proteins. They have been shown to be highly effective, in some cases more so than detergent micelles, at maintaining the structural integrity of membrane proteins in solution, and have shown promi...

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Detalles Bibliográficos
Autores principales: Watkinson, Thomas G., Calabrese, Antonio N., Ault, James R., Radford, Sheena E., Ashcroft, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174144/
https://www.ncbi.nlm.nih.gov/pubmed/27343183
http://dx.doi.org/10.1007/s13361-016-1421-1