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Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6

Mitogen inducible gene-6 (Mig-6) is a feedback inhibitor of epidermal growth factor receptor (EGFR) signaling pathway. The liver-specific knockout mice of the Mig-6 gene (Mig-6(d/d)) showed hepatomegaly and increased hypercholesterolemia. In this study, the biomarkers of insulin resistance and the e...

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Detalles Bibliográficos
Autores principales: Park, Byung Kil, Lee, Eun-Ah, Kim, Hee-Youn, Lee, Jun Choul, Kim, Koon Soon, Jeong, Won Hoon, Kim, Ki Young, Ku, Bon Jeong, Rhee, Sang Dal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174183/
https://www.ncbi.nlm.nih.gov/pubmed/28053990
http://dx.doi.org/10.1155/2016/1632061