Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep

Human skin has evolved rapidly, leaving evolutionary signatures in the genome. The filaggrin (FLG) gene is widely studied for its skin-barrier function in humans. The extensive genetic variation in this gene, especially common loss-of-function (LoF) mutations, has been established as primary risk fa...

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Detalles Bibliográficos
Autores principales: Eaaswarkhanth, Muthukrishnan, Xu, Duo, Flanagan, Colin, Rzhetskaya, Margarita, Hayes, M. Geoffrey, Blekhman, Ran, Jablonski, Nina G., Gokcumen, Omer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174745/
https://www.ncbi.nlm.nih.gov/pubmed/27678121
http://dx.doi.org/10.1093/gbe/evw242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174745/
https://www.ncbi.nlm.nih.gov/pubmed/27678121
http://dx.doi.org/10.1093/gbe/evw242

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