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Unexplained lymphadenopathies: autoimmune lymphoproliferative syndrome in an adult patient

Autoimmune lymphoproliferative syndrome (ALPS) is characterised by massive enlargement of the lymphoid organs, autoimmune cytopenias and a predisposition to develop lymphoid malignancies. The basic defect is a disturbance of the lymphocyte apoptosis, and a high number of circulating TCRab CD3(+)CD4(...

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Detalles Bibliográficos
Autores principales: Leal-Seabra, Fatima, Costa, Gonçalo Sarmento, Coelho, Henrique Pereira, Oliveira, Agripino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174767/
https://www.ncbi.nlm.nih.gov/pubmed/27979843
http://dx.doi.org/10.1136/bcr-2016-216758