BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53

The acquisition of drug resistance is a persistent clinical problem limiting the successful treatment of glioblastoma (GBM). However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. In this study, we report that BACH1, a hem...

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Detalles Bibliográficos
Autores principales: Nie, Er, Jin, Xin, Wu, Weining, Yu, Tianfu, Zhou, Xu, Zhi, Tongle, Shi, Zhumei, Zhang, Junxia, Liu, Ning, You, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175153/
https://www.ncbi.nlm.nih.gov/pubmed/28000777
http://dx.doi.org/10.1038/srep39743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175153/
https://www.ncbi.nlm.nih.gov/pubmed/28000777
http://dx.doi.org/10.1038/srep39743

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