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Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS

The comparison of extraction methods for global metabolomics is usually executed in biofluids only and focuses on metabolite coverage and method repeatability. This limits our detailed understanding of extraction parameters such as recovery and matrix effects and prevents side-by-side comparison of...

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Detalles Bibliográficos
Autores principales: Sitnikov, Dmitri G., Monnin, Cian S., Vuckovic, Dajana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175266/
https://www.ncbi.nlm.nih.gov/pubmed/28000704
http://dx.doi.org/10.1038/srep38885