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Overexcited MaxiK and K(ATP) channels underlie obstructive jaundice-induced vasoconstrictor hyporeactivity of arterial smooth muscle
Substantial evidence has shown that obstructive jaundice can induce vascular hyporesponsiveness. The present study was designed to investigate mechanisms of MaxiK channel and K(ATP) underlying cholestasis-induced vascular dysfunction. The isolated thoracic aorta was used to explore norepinephrine (N...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175282/ https://www.ncbi.nlm.nih.gov/pubmed/28000721 http://dx.doi.org/10.1038/srep39246 |