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Overexcited MaxiK and K(ATP) channels underlie obstructive jaundice-induced vasoconstrictor hyporeactivity of arterial smooth muscle

Substantial evidence has shown that obstructive jaundice can induce vascular hyporesponsiveness. The present study was designed to investigate mechanisms of MaxiK channel and K(ATP) underlying cholestasis-induced vascular dysfunction. The isolated thoracic aorta was used to explore norepinephrine (N...

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Detalles Bibliográficos
Autores principales: Yuan, Ya-wei, Wang, Long, Lu, Zhan-ying, Long, Yue, Jiao, Ying-fu, Xia, Qiang, Wen, Da-xiang, Yu, Wei-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175282/
https://www.ncbi.nlm.nih.gov/pubmed/28000721
http://dx.doi.org/10.1038/srep39246