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The presence of T cell epitopes is important for induction of antibody responses against antigens directed to DEC205(+) dendritic cells
In vivo antigen targeting to dendritic cells (DCs) has been used as a way to improve immune responses. Targeting is accomplished with the use of monoclonal antibodies (mAbs) to receptors present on the DC surface fused with the antigen of interest. An anti-DEC205 mAb has been successfully used to ta...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175286/ https://www.ncbi.nlm.nih.gov/pubmed/28000705 http://dx.doi.org/10.1038/srep39250 |