The presence of T cell epitopes is important for induction of antibody responses against antigens directed to DEC205(+) dendritic cells

In vivo antigen targeting to dendritic cells (DCs) has been used as a way to improve immune responses. Targeting is accomplished with the use of monoclonal antibodies (mAbs) to receptors present on the DC surface fused with the antigen of interest. An anti-DEC205 mAb has been successfully used to ta...

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Detalles Bibliográficos
Autores principales: Amorim, Kelly N. S., Rampazo, Eline V., Antonialli, Renan, Yamamoto, Marcio M., Rodrigues, Mauricio M., Soares, Irene S., Boscardin, Silvia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175286/
https://www.ncbi.nlm.nih.gov/pubmed/28000705
http://dx.doi.org/10.1038/srep39250

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