Increased T cell breadth and antibody response elicited in prime-boost regimen by viral vector encoded homologous SIV Gag/Env in outbred CD1 mice

BACKGROUND: A major obstacle for the development of HIV vaccines is the virus’ worldwide sequence diversity. Nevertheless, the presence of T cell epitopes within conserved regions of the virus’ structural Gag protein and conserved structures in the envelope (env) sequence raises the possibility that...

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Detalles Bibliográficos
Autores principales: Andersson, Anne-Marie Carola, Holst, Peter Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175304/
https://www.ncbi.nlm.nih.gov/pubmed/27998269
http://dx.doi.org/10.1186/s12967-016-1102-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175304/
https://www.ncbi.nlm.nih.gov/pubmed/27998269
http://dx.doi.org/10.1186/s12967-016-1102-7

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