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S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells

MicroRNAs (miRNAs) are short non-coding RNAs that silence mRNAs. They are generated following transcription and cleavage by the DROSHA/DGCR8 and DICER/TRBP/PACT complexes. Although it is known that components of the miRNA biogenesis machinery can be phosphorylated, it remains poorly understood how t...

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Detalles Bibliográficos
Autores principales: Warner, Matthew J., Bridge, Katherine S., Hewitson, James P., Hodgkinson, Michael R., Heyam, Alex, Massa, Bailey C., Haslam, Jessica C., Chatzifrangkeskou, Maria, Evans, Gareth J.O., Plevin, Michael J., Sharp, Tyson V., Lagos, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175334/
https://www.ncbi.nlm.nih.gov/pubmed/27407113
http://dx.doi.org/10.1093/nar/gkw631