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S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells
MicroRNAs (miRNAs) are short non-coding RNAs that silence mRNAs. They are generated following transcription and cleavage by the DROSHA/DGCR8 and DICER/TRBP/PACT complexes. Although it is known that components of the miRNA biogenesis machinery can be phosphorylated, it remains poorly understood how t...
Autores principales: | Warner, Matthew J., Bridge, Katherine S., Hewitson, James P., Hodgkinson, Michael R., Heyam, Alex, Massa, Bailey C., Haslam, Jessica C., Chatzifrangkeskou, Maria, Evans, Gareth J.O., Plevin, Michael J., Sharp, Tyson V., Lagos, Dimitris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175334/ https://www.ncbi.nlm.nih.gov/pubmed/27407113 http://dx.doi.org/10.1093/nar/gkw631 |
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