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Differential peak calling of ChIP-seq signals with replicates with THOR

The study of changes in protein–DNA interactions measured by ChIP-seq on dynamic systems, such as cell differentiation, response to treatments or the comparison of healthy and diseased individuals, is still an open challenge. There are few computational methods comparing changes in ChIP-seq signals...

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Detalles Bibliográficos
Autores principales: Allhoff, Manuel, Seré, Kristin, F. Pires, Juliana, Zenke, Martin, G. Costa, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175345/
https://www.ncbi.nlm.nih.gov/pubmed/27484474
http://dx.doi.org/10.1093/nar/gkw680