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VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation

The major human pathogen Mycobacterium tuberculosis can survive in the host organism for decades without causing symptoms. A large cohort of Toxin–Antitoxin (TA) modules contribute to this persistence. Of these, 48 TA modules belong to the vapBC (virulence associated protein) gene family. VapC toxin...

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Detalles Bibliográficos
Autores principales: Winther, Kristoffer, Tree, Jai J., Tollervey, David, Gerdes, Kenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175351/
https://www.ncbi.nlm.nih.gov/pubmed/27599842
http://dx.doi.org/10.1093/nar/gkw781