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Evolution of Arabidopsis protection of telomeres 1 alters nucleic acid recognition and telomerase regulation

Protection of telomeres (POT1) binds chromosome ends, recognizing single-strand telomeric DNA via two oligonucleotide/oligosaccharide binding folds (OB-folds). The Arabidopsis thaliana POT1a and POT1b paralogs are atypical: they do not exhibit telomeric DNA binding, and they have opposing roles in r...

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Detalles Bibliográficos
Autores principales: Arora, Amit, Beilstein, Mark A., Shippen, Dorothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175356/
https://www.ncbi.nlm.nih.gov/pubmed/27651456
http://dx.doi.org/10.1093/nar/gkw807