Protein–DNA interfaces: a molecular dynamics analysis of time-dependent recognition processes for three transcription factors

We have studied the dynamics of three transcription factor–DNA complexes using all-atom, microsecond-scale MD simulations. In each case, the salt bridges and hydrogen bond interactions formed at the protein–DNA interface are found to be dynamic, with lifetimes typically in the range of tens to hundr...

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Detalles Bibliográficos
Autores principales: Etheve, Loïc, Martin, Juliette, Lavery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175364/
https://www.ncbi.nlm.nih.gov/pubmed/27658967
http://dx.doi.org/10.1093/nar/gkw841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175364/
https://www.ncbi.nlm.nih.gov/pubmed/27658967
http://dx.doi.org/10.1093/nar/gkw841

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