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Protein–DNA interfaces: a molecular dynamics analysis of time-dependent recognition processes for three transcription factors
We have studied the dynamics of three transcription factor–DNA complexes using all-atom, microsecond-scale MD simulations. In each case, the salt bridges and hydrogen bond interactions formed at the protein–DNA interface are found to be dynamic, with lifetimes typically in the range of tens to hundr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175364/ https://www.ncbi.nlm.nih.gov/pubmed/27658967 http://dx.doi.org/10.1093/nar/gkw841 |